Men’s Sexual Arousal

Neurochemical Solutions for Arousal and Desire

The dopamine connection: stimulating desire and motivation.

Understanding How Arousal Impacts Erectile Performance

Erectile function depends on more than circulation—it begins in the brain. Sexual arousal triggers a complex neurological and vascular response involving hormones, neurotransmitters, and emotional connection. When this mind–body communication is disrupted, it can affect erection quality, stamina, and satisfaction, even in otherwise healthy men.

When Physical Function Is Intact but Mental Stimulation Falters

For some men, erectile challenges aren’t due to vascular issues but to diminished arousal signals from the brain. Stress, anxiety, fatigue, and hormonal changes can all reduce dopamine—the neurotransmitter responsible for sexual desire and motivation. When arousal decreases, achieving or maintaining an erection becomes more difficult, regardless of physical health.

Neurochemical Solutions for Arousal and Desire

Advanced medications and peptides can help restore the brain’s natural arousal signals, improving both mental and physical aspects of performance. At Nexa, we specialize in physician-guided treatments that safely stimulate dopamine and melanocortin receptors to enhance desire, increase sexual responsiveness, and strengthen erectile function from the inside out.

Super Sexy Spray (PT-141 + Oxytocin)

Super Sexy Spray  combines cutting-edge peptide science with the power of confidence and connection. Formulated with PT-141 (Bremelanotide) to heighten desire and Oxytocin to enhance emotional intimacy, this fast-acting nasal spray helps men feel more energized, responsive, and connected to their partner. Designed to boost both physical performance and emotional closeness, Super Sexy Spray empowers men to experience deeper satisfaction and revitalized passion.

Melanotan 2 Injectable

Melanotan 2  is a powerful peptide designed to enhance natural tanning, boost confidence, and elevate mood and desire. This injectable formula stimulates melanin production for a deeper, more even skin tone while also supporting increased energy and libido. Safe, effective, and physician-guided, Melanotan II helps men look and feel their best—inside and out.

PT-141  Injectable

PT-141 (Bremelanotide)  is a cutting-edge peptide treatment designed to naturally enhance sexual performance and desire. Unlike traditional ED medications, PT-141 works through the brain’s arousal pathways—boosting libido, stamina, and satisfaction without relying on blood flow alone. Safe, effective, and physician-guided, PT-141 helps men reignite confidence, passion, and peak performance in every aspect of intimacy.

Apomorphine: A Physician-Guided Option to Reignite Arousal

Apomorphine is a dopamine-activating treatment that enhances sexual arousal and responsiveness. When combined with other ED medications, it can amplify results—improving erection quality, desire, and overall satisfaction. This synergistic approach targets both the mind and body, helping men experience stronger performance, increased confidence, and a more natural, spontaneous response.

INCREASE YOUR GIRTH & LENGTH UP TO 1” (OR MORE) WITHOUT SURGERY

P-Long® and BIGGER® are clinically backed, non-surgical protocols designed to safely enhance penis size, strength, and performance. Using a customized blend of PRP, peptides, and at-home therapy, they help men achieve natural, lasting improvement in both length and girth—while also boosting confidence and sexual wellness.

OPTIMIZE TODAY, OWN TOMORROW.

OPTIMIZE TODAY, OWN TOMORROW.

OPTIMIZE TODAY, OWN TOMORROW.

OPTIMIZE TODAY, OWN TOMORROW.

OPTIMIZE TODAY, OWN TOMORROW.

OPTIMIZE TODAY, OWN TOMORROW.

Frequently Asked Questions

  • How does arousal affect erectile performance?

    Arousal begins in the brain—it’s the neurological signal that triggers blood flow and physical response. When dopamine and other neurotransmitters responsible for desire are low, achieving or maintaining an erection can become more difficult, even if circulation and hormone levels are normal. Addressing both physical and mental stimulation is key to restoring full sexual function.

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  • What causes low arousal or decreased sexual desire in men?

    Low arousal can stem from stress, anxiety, fatigue, medication side effects, hormonal changes, or reduced dopamine activity in the brain. Over time, these factors can disconnect the mental and physical aspects of sexual response. Nexa Med Spa identifies the root cause and tailors treatment to reignite natural desire and confidence.

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  • How do Apomorphine and these peptides help with arousal and erectile function?

    Apomorphine activates dopamine receptors in the brain to enhance sexual motivation and arousal, while these peptides stimulate melanocortin receptors that directly increase libido. Together or separately, these therapies help bridge the gap between mental desire and physical performance—improving both arousal and erection quality.

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  • How are these treatments different from Viagra® or Cialis®?

    Viagra®, Cialis®, and other PDE5 inhibitors primarily work by increasing blood flow to the penis, supporting the physical aspect of erections. Apomorphine and these peptides, on the other hand, target the brain’s arousal pathways, addressing the mental and emotional components of sexual response. For many men, combining these treatments delivers more complete, satisfying results.

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  • Are Apomorphine and these peptides safe?

    Yes—when prescribed and monitored by a licensed medical provider. Both treatments have been clinically studied and are safe for most men when used as directed. Nexa’s physicians will review your medical history, discuss your goals, and determine which therapy—or combination—is right for you.

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  • How quickly do these treatments work?

    Apomorphine typically works within 15–30 minutes, while peptides may take 30–60 minutes to reach full effect. Some men notice improved responsiveness after just one use, while others benefit most from consistent, guided treatment.

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  • Can Apomorphine or these peptides be used alongside other ED medications or treatments?

    Yes—many men see the best results when combining arousal-enhancing medications with blood-flow-focused therapies such as Viagra®, Cialis®, Trimix, or regenerative options like P-Long® and BIGGER™. Nexa’s team will personalize your protocol to ensure safe, synergistic results.

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