hCG

hCG-Supported Weight Management

Evidence-Aware. Clinician-Guided. Precisely Personalized.

What Is hCG?

hCG is a naturally occurring hormone. In medicine, it’s used for fertility and certain endocrine indications. While some programs market hCG for weight loss, the FDA has not approved hCG for weight loss, and evidence for efficacy is mixed. If considered at Nexa, hCG is used only within a broader, clinician-supervised program focused on balanced nutrition, adequate protein, resistance training, and realistic calorie targets.

How hCG Is Positioned in Weight Management

Our goal is to protect health while supporting body-composition change. In select cases, a clinician may discuss hCG as an adjunct with potential aims to:

  • Support adherence to a structured plan
  • Help preserve lean mass during a calorie deficit (paired with protein and strength training)
  • Provide short-term structure within a comprehensive program

We do not promote very-low-calorie diets. All programs prioritize metabolic health, sustainable habits, and informed consent.

Who It’s For

You may discuss hCG with your provider if you:

  • Seek a closely supervised program with frequent check-ins and labs
  • Want a short, structured phase to complement lifestyle change
  • Need a non-stimulant adjunct and have not met goals with lifestyle alone

Eligibility is determined after a medical evaluation, medication review, and baseline labs.

Your hCG Program at Nexa

  • Clinical Consult & Labs – Medical history, medications, cardiometabolic markers, and goals.
  • Clear Education & Consent – Transparent discussion of off-label use and FDA stance.
  • Balanced Nutrition Plan – Moderate calorie targets, adequate protein, hydration, and micronutrients.
  • Strength & Movement – Resistance training to help preserve lean mass; daily activity goals.
  • Ongoing Monitoring – Weight, waist, body composition, energy, and side-effect checks; dose and plan adjustments.
  • Transition & Maintenance – Step-down strategy to sustain results without rebound.

hCG vs. GLP-1/GLP-2 Therapies

  • hCG (off-label for weight): Considered as an adjunct for short, structured phases with close monitoring; evidence for weight loss is mixed; not FDA-approved for this use.
  • GLP-1/GLP-2 (Semaglutide, Tirzepatide): FDA-approved for chronic weight management in indicated patients; robust evidence for appetite regulation, glycemic balance, and fat loss.

Approach: We prioritize therapies with the strongest evidence base and may consider hCG only when clinically appropriate and fully informed.

OPTIMIZE TODAY, OWN TOMORROW.

OPTIMIZE TODAY, OWN TOMORROW.

OPTIMIZE TODAY, OWN TOMORROW.

OPTIMIZE TODAY, OWN TOMORROW.

OPTIMIZE TODAY, OWN TOMORROW.

OPTIMIZE TODAY, OWN TOMORROW.

Frequently Asked Questions

  • Is hCG FDA-approved for weight loss?

    No. hCG is approved for fertility and certain endocrine uses—not for weight loss. Any use for weight management is off-label.

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  • Will I need an extreme low-calorie diet?

    No. Nexa does not use very-low-calorie protocols. We set sustainable calorie targets with adequate protein and strength training.

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  • How long does an hCG phase last?

    If used, phases are short and supervised (often several weeks) with a defined transition to maintenance.

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  • Can hCG be combined with GLP-1 or other therapies?

    Possibly—based on your health profile. Your clinician may recommend alternatives with stronger evidence first.

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  • What monitoring is required?

    Baseline and periodic labs, symptom reviews, body-composition tracking, and structured follow-ups.

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  • Is medical weight loss safe?

    Yes. All programs are physician-supervised and based on your medical history, labs, and goals. Ongoing monitoring ensures safe, effective, and sustainable results.

  • Who should avoid using the hCG?

    hCG is not FDA-approved for weight loss. Use only under clinician supervision.

    Not appropriate if you:

    • Are pregnant, trying to conceive, or breastfeeding
    • Have hormone-sensitive cancers (e.g., breast, prostate) or unexplained vaginal bleeding
    • Have a history of thromboembolic disease (blood clots) or significant cardiovascular risk without clearance
    • Have uncontrolled thyroid or adrenal disorders
    • Have severe liver or kidney disease
    • Have known hypersensitivity to hCG or formulation components

    Use with caution if you:

    • Have PCOS, endometriosis, or gynecologic conditions (risk/benefit must be individualized)
    • Are at risk for electrolyte imbalance or dehydration
    • Take medications that may interact with hormones or fluid balance
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  • What are the possible side effects with hCG?

    Common:

    Injection-site irritation, headache, mood changes, fatigue, water retention

    Less common:

    Gynecomastia (men), acne or breast tenderness, edema, blood pressure shifts

    Rare/serious (seek care):

    Thromboembolic events (leg swelling/pain, chest pain, shortness of breath)

    Visual changes, severe abdominal pain

    Ovarian hyperstimulation in fertility settings (discuss risks if applicable)

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