Trimix Injections

Trimix Injections: Powerful, Targeted Treatment for Erectile Dysfunction

A physician-guided solution for stronger, more reliable erections.

What is Trimix?

For men who don’t achieve the desired results from oral medications like Viagra®, Cialis®, or Levitra®, Trimix injections offer a fast-acting, highly effective alternative. Administered under medical supervision, Trimix delivers a customized combination of three proven medications directly to the treatment area—improving blood flow and helping men achieve firm, natural-feeling erections with consistency and confidence.

How Trimix Works to Restore Natural Performance

Trimix is a compounded injection that contains three key medications—alprostadil, papaverine, and phentolamine—that work together to relax blood vessels and increase circulation to the penis. This direct approach produces a rapid response, often within minutes, regardless of psychological or vascular challenges that may interfere with erectile function.

Benefits of Trimix Therapy

  • Works quickly—often within 5–15 minutes

  • Produces natural-feeling, longer-lasting erections

  • Effective when oral medications are ineffective

  • Physician-guided dosing for precision and safety

  • Can be combined with other regenerative treatments for enhanced results

What to Expect During Treatment

Your Trimix journey at Nexa begins with a private consultation and a detailed medical assessment. Our trained providers will teach you proper self-administration techniques for convenience and discretion. Most men experience significant improvement after their first treatment, with minimal discomfort and predictable results.

Want to increase your girth and length up to 1” (or more) without surgery?

P-Long® and BIGGER™ are non-surgical protocols designed to safely enhance penis size, strength, and performance. Using a customized blend of PRP, peptides, and at-home therapy, they help men achieve natural, lasting improvement in both length and girth—while also boosting confidence and sexual wellness.

OPTIMIZE TODAY, OWN TOMORROW.

OPTIMIZE TODAY, OWN TOMORROW.

OPTIMIZE TODAY, OWN TOMORROW.

OPTIMIZE TODAY, OWN TOMORROW.

OPTIMIZE TODAY, OWN TOMORROW.

OPTIMIZE TODAY, OWN TOMORROW.

Frequently Asked Questions

  • What is Trimix, and how does it work?

    Trimix is a physician-prescribed injectable treatment for erectile dysfunction that combines three proven medications—alprostadil, papaverine, and phentolamine—to improve blood flow and help achieve firm, long-lasting erections. Unlike oral medications, Trimix is injected directly into the treatment area, providing fast, targeted results.

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  • How quickly does Trimix work?

    Trimix typically takes effect within 5 to 15 minutes and can last from 30 minutes to over an hour, depending on dosage and individual response. Because it works locally, Trimix bypasses the digestive system, making it highly reliable for men who don’t respond to pills.


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  • Is Trimix safe?

    Yes. When prescribed and monitored by a qualified provider, Trimix is safe and well-tolerated. Nexa’s medical professionals ensure your dosage is personalized to your needs and teach you proper self-administration techniques for accuracy, safety, and comfort.

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  • Who is a good candidate for Trimix injections?

    Trimix is ideal for men who have not achieved satisfactory results with oral ED medications like Viagra®, Cialis®, or Levitra®. It’s also an excellent option for those who prefer a fast-acting, predictable, and non-systemic treatment for erectile dysfunction.

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  • Does Trimix hurt?

    Most men report minimal discomfort during injection, similar to a small pinch. The procedure is quick, and Nexa’s expert providers ensure you’re properly trained to administer it safely and comfortably at home.

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  • Are there any side effects?

    Side effects are uncommon and typically mild. Some men may experience slight bruising, redness, or minor aching at the injection site. Serious side effects are rare but can include prolonged erections (priapism), which should be reported immediately. Nexa’s providers monitor your treatment closely to ensure safety.

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  • How is Trimix different from oral ED medications?

    Trimix acts directly at the site of action, making it more effective for men who don’t respond to pills. It works faster, lasts longer, and avoids systemic side effects like headaches or indigestion that can occur with oral medications.

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