Bella
The Bella Cocktail for Medical Weight Loss
Metabolic Balance. Appetite Control. Elevated Energy.


What Is the Nexa Bella Cocktail?
Nexa’s Bella Cocktail is a compounded, physician-prescribed combination therapy that brings together clinically proven medications and essential nutrients to target multiple facets of weight management.
Each formulation may include:
- Metformin – Improves insulin sensitivity, stabilizes blood sugar, and supports metabolic health.
- Topiramate – Reduces appetite, curbs cravings, and helps control portion sizes.
- Bupropion – Supports focus, motivation, and emotional balance, helping to regulate reward-based eating.
- Naltrexone – Modulates the brain’s reward system to reduce cravings and emotional triggers around food.
- Vitamin B12 – Boosts cellular energy, supports metabolism, and enhances overall vitality.
Together, these components help the body achieve
better appetite control, improved energy, and more efficient fat metabolism—without the use of stimulants.
How the Bella Cocktail Works
This advanced combination therapy works across several biological systems to promote healthy, sustainable weight loss:
- Regulates appetite and cravings through central nervous system pathways.
- Improves insulin function and glucose metabolism to reduce fat storage.
- Balances mood and energy to help maintain motivation and consistency.
- Enhances metabolic efficiency for steady, sustainable fat loss.
- Supports nutrient optimization with B12 for energy and recovery.
The Bella Cocktail is designed to
address the root causes of weight resistance—supporting both body and mind for balanced, long-term success.


Who It’s For
The Bella Cocktail may be ideal for individuals who:
- Struggle with cravings or emotional eating
- Experience slow metabolism or insulin resistance
- Prefer a non-stimulant, multi-mechanism approach to weight loss
- Want to improve energy, mood, and metabolic health simultaneously
- Seek a customized program that can stand alone or complement GLP-based therapies
Eligibility is determined through a comprehensive consultation and medical review.
Benefits of the Bella Cocktail
- Multi-pathway approach targeting metabolism, appetite, and energy
- Non-stimulant formulation for steady, sustainable results
- Enhanced focus and mood for better adherence and motivation
- Balanced glucose regulation and insulin sensitivity
- Improved fat metabolism and appetite control
- Vitamin B12 boost for sustained energy and cellular health


Your Bella Cocktail Program at Nexa
- Comprehensive Evaluation – Your provider will assess your health history, metabolism, and weight loss goals.
- Customized Formulation – Dosages of each ingredient are personalized to match your individual needs and tolerability.
- Medical Oversight – Your plan is closely monitored for safety, progress, and long-term success.
- Integrated Support – Nutritional guidance, lab monitoring, and optional GLP or peptide therapies for enhanced synergy.
- Ongoing Optimization – Regular follow-ups to fine-tune your regimen and sustain momentum.
Bella Cocktail vs. GLP-Based Therapies
- Bella Cocktail: Addresses cravings, metabolism, insulin sensitivity, and energy through multiple mechanisms—ideal for clients seeking comprehensive, non-injectable options.
- GLP-1 & GLP-2 Therapies (Semaglutide, Tirzepatide): Focus primarily on appetite regulation and metabolic balance through hormonal pathways.
- Together: These treatments can complement each other beautifully, with Bella enhancing energy and mood while GLP therapies promote deep metabolic regulation.

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Frequently Asked Questions
Is the Bella Cocktail FDA-approved?
BOOK NOWThe Bella Cocktail is a compounded prescription formulation, meaning it is customized and prescribed by physicians using FDA-approved ingredients for off-label combination therapy.
How is the Bella Cocktail taken?
BOOK NOWMost patients take it orally, typically once or twice daily, depending on their personalized prescription and response.
How long before I notice results?
BOOK NOWMost clients notice improved appetite control and energy within 2–4 weeks, with visible changes in body composition often appearing within 8–12 weeks.
Can it be combined with GLP-1 medications or peptides?
BOOK NOWYes. Many clients achieve enhanced results by pairing the Bella Cocktail with Semaglutide, Tirzepatide, or AOD-9604, based on their goals and provider recommendations.
Will it make me feel jittery or overstimulated?
BOOK NOWNo. The Bella Cocktail is a non-stimulant formulation designed for balanced, steady energy and mood support.
Is medical weight loss safe?
Yes. All programs are physician-supervised and based on your medical history, labs, and goals. Ongoing monitoring ensures safe, effective, and sustainable results.
Who should avoid using the Bella Cockatil?
BOOK NOWThe Bella Cocktail may not be appropriate if you:
- Are pregnant, planning to become pregnant, or breastfeeding
- Have a history of seizure disorders or epilepsy (due to Bupropion and Topiramate)
- Are currently taking opioid medications or receiving opioid therapy (Naltrexone can block opioid effects and cause withdrawal)
- Have uncontrolled high blood pressure or significant cardiovascular disease
- Have moderate-to-severe kidney or liver impairment (Metformin and Topiramate require caution or dose adjustment)
- Have a history of metabolic acidosis or kidney stones (Topiramate-related risk)
- Are taking MAO inhibitors or certain antidepressants that interact with Bupropion
- Have uncontrolled psychiatric conditions, such as bipolar disorder or major depression, without medical clearance
- Have a known allergy or hypersensitivity to any of the ingredients
Use with caution if you:
- Are following a ketogenic diet (may increase acidosis risk)
- Have a history of anxiety, insomnia, or mood changes
- Have vitamin B12 deficiency or pernicious anemia (your provider may adjust your formulation)
- Consume large amounts of alcohol (can increase liver and seizure risks)
What are the possible side effects with the Bella Cocktail?
Common or Mild Side Effects
- Digestive changes: mild nausea, loose stool, or stomach upset (commonly from Metformin)
- Taste alteration or tingling sensation: Topiramate-related, usually in fingers, toes, or around the mouth
- Dry mouth or mild headache
- Insomnia or restlessness: Bupropion-related, often improves after the first few weeks
- Mild fatigue or dizziness
- Temporary decrease in appetite or change in food preferences
- Flushing or warmth from Vitamin B12 injection or supplement
Less Common or Moderate Side Effects
- Your provider monitors for these effects and adjusts your plan as needed:
- Mood changes (mild anxiety, irritability, or low mood) — typically dose-related
- Increased heart rate or blood pressure (usually mild and transient)
- Kidney stone formation (rare, related to Topiramate; hydration helps reduce risk)
- Changes in concentration or “foggy” thinking at higher Topiramate doses
- Metallic taste in mouth (Metformin-related)
- Constipation or bloating


