NAD+

• Boosts Cellular Energy: NAD+ is vital for ATP production within the mitochondria, increasing cellular energy and reducing fatigue by improving mitochondrial function.
• Repairs DNA: By activating PARPs, NAD+ supports DNA repair mechanisms, protecting against age-related damage, oxidative stress, and potentially lowering cancer risk.
• Promotes Healthy Aging: NAD+ supplementation enhances longevity and supports healthier aging by improving metabolic functions and boosting sirtuin activity, which regulates stress resistance and cell survival.
• Enhances Cognitive Function: Clinical trials indicate NAD+ can improve memory, attention, and overall cognitive performance in elderly patients experiencing age-related cognitive decline.
• Improves Metabolic Health: NAD+ supplementation shows promise in improving insulin sensitivity, reducing inflammation, and managing conditions like obesity and type 2 diabetes, leading to better metabolic markers and reduced fat accumulation.

• Active Cancer: Consult a healthcare provider before using NAD+ if you have active cancer.
• Pregnancy and Breastfeeding: The safety of NAD⁺ for pregnant or breastfeeding women has not been established.
• Liver or Kidney Disease: Seek medical advice before starting NAD+ therapy if you have liver or kidney conditions.

• Injection Site Reactions: Minor swelling or redness may occur. Rotate injection sites to prevent irritation.
• Immediate Discomfort: Immediately following the injection, some individuals may experience a fleeting flush, mild heart palpitations, or a sensation of tightness. These are due to rapid cellular reactions and a temporary metabolic shift, usually resolving within 30 minutes.
• Gastrointestinal Issues: Mild nausea, stomach discomfort, or diarrhea may occur, particularly when initiating treatment at higher doses.
• Headaches and Fatigue: As the body adapts to NAD+'s influence on cellular energy and blood flow, some users may report temporary headaches or fatigue.

• Start with a Low Dose: Begin with a minimal dose to determine your body's tolerance.
• Stay Hydrated: Drink plenty of water to mitigate side effects like headaches and nausea, as proper hydration supports cellular function and detoxification.
• Rotate Injection Sites: Varying injection sites helps to prevent irritation or bruising in any one area.
• Take it Slowly: ​Administer the injection slowly to minimize discomfort.

When to Contact Us (Seek Medical Advice if You Experience):

• Fever of 100.4°F (38°C) or higher
• Blistering at the injection site
• Muscle aches, nausea, dizziness, or headache
• Skin rash, severe itching, vomiting, or hives

• Nicotinamide adenine dinucleotide (NAD+) is an energizing coenzyme vital to numerous bodily processes. It is crucial for converting food into energy, regulating DNA repair, and enhancing immune system function.
• Primarily, NAD+ acts as a coenzyme in redox reactions, facilitating the transfer of electrons and hydrogen in metabolic pathways like glycolysis, the citric acid cycle, and oxidative phosphorylation. It also serves as a substrate for enzymes such as sirtuins and poly ADP-ribose polymerases (PARPs). These enzymes are essential for regulating DNA repair, gene expression, and cellular stress responses. Sirtuins, in particular, utilize NAD+ to remove acetyl groups from proteins, influencing metabolism, inflammation, and stress resistance.
• NAD+ therapy aims to boost overall energy, support cognitive function, and promote healthy aging by enhancing mitochondrial health. By replenishing declining NAD+ levels, this supplementation seeks to restore essential cellular functions and improve overall metabolic health.

• 1-2 Weeks: Users commonly experience an increase in energy, improved focus, enhanced mood, and reduced fatigue, as mitochondrial function begins to improve.
• 4-6 Weeks: Noticeable improvements in cognitive functions, such as memory and attention, become more apparent.
• 8-12 Weeks: Full benefits related to metabolic health emerge, including enhanced physical endurance, reduced inflammation, and improved insulin sensitivity. Clinical studies during this period demonstrate a significant decrease in markers of aging and metabolic stress.
• Long-term: Consistent NAD+ supplementation supports longevity, increases skin elasticity, and lowers the risk of age-related diseases. Users report sustained improvements in overall vitality and mental and physical well-being.