MOTS-C

• Enhanced Metabolic Function: MOTS-C improves the body's glucose utilization and insulin sensitivity, leading to better blood sugar regulation and reduced insulin resistance. This is beneficial for managing metabolic disorders and promoting long-term health.
• Improved Physical Performance: Studies show MOTS-C enhances endurance and muscle function by boosting mitochondrial efficiency. It increases running distance and power output, helping to maintain muscle mass and performance, especially during aging or periods of metabolic stress.
• Fat Reduction: MOTS-C supports fat burning and prevents weight gain without affecting muscle mass. It increases fat metabolism, promoting a leaner body composition and aiding in weight management.
• Reduced Inflammation: It helps decrease inflammation and oxidative stress throughout the body, supporting overall health and the body’s natural anti-inflammatory processes.
• Bone Health: MOTS-C promotes bone growth and helps prevent bone loss, offering benefits for conditions like osteoporosis, particularly in postmenopausal women.
• Longevity Benefits: By maintaining mitochondrial health, improving metabolic flexibility, and reducing systemic inflammation, MOTS-C contributes to healthier aging, enhanced physical endurance, and an improved quality of life.

• MOTS-C is not recommended for individuals with active cancer unless advised by a healthcare provider. 
• Pregnant or breastfeeding women should also avoid these peptides due to insufficient safety data.

• Injection Site Reactions: Mild redness, itching, or discomfort may occur at the injection site. Rotating the injection site can help minimize these symptoms.
• Headache and Dizziness: These have been reported, possibly due to increased mitochondrial activity and altered blood flow.
• Mild Gastrointestinal Distress: Nausea or stomach discomfort may occur, especially at higher doses, but these symptoms are usually mild and temporary.
• Flushing and Fatigue: Temporary fatigue or flushing may occur due to increased metabolic activity from AMPK activation.

When to Contact Us (Seek Medical Advice if You Experience):

• Fever of 100.4°F (38°C) or higher
• Blistering at the injection site
• Muscle aches, nausea, dizziness, or headache
• Skin rash, severe itching, vomiting, or hives

• Start with a Low Dose: Begin with a smaller dose and gradually increase it to minimize potential side effects such as nausea and headaches.
• Vary Injection Sites: Rotate injection locations to prevent irritation and pain in any single area.
• Maintain Hydration: Ensure adequate water intake to help reduce headaches and flushing, as proper hydration supports mitochondrial function.
• Administer with Food: If you experience gastrointestinal discomfort, taking MOTS-C with food may help alleviate these symptoms.
• Consult a Healthcare Provider: Regular professional monitoring is recommended to ensure safe and effective use.

• MOTS-C is a 16-amino acid peptide derived from the mitochondrial genome's 12S rRNA gene. It plays a crucial role in cellular energy and stress responses by activating the AMPK pathway, a primary regulator of mitochondrial function.
• In response to metabolic stressors like glucose restriction or oxidative stress, MOTS-C translocates to the nucleus. There, it regulates gene expression related to stress resistance, enhancing glucose uptake, fatty acid oxidation, and metabolic flexibility to maintain energy homeostasis. 
• Additionally, MOTS-C’s ability to regulate stress-response transcription factors helps reduce inflammation and preserve mitochondrial integrity, promoting overall cellular health and longevity.

• 1-2 Weeks: Users may experience improved energy levels and reduced fatigue as mitochondrial function and metabolism begin to improve.
• 4-6 Weeks: Noticeable improvements in physical performance, endurance, and stamina can be observed. Studies demonstrate increased running distance and time, indicating enhanced muscle and mitochondrial efficiency. Users may also experience reduced inflammation and an overall improvement in physical and mental well-being.
• Long-Term: Prolonged use of MOTS-C can significantly enhance mitochondrial health, promote bone density, and optimize overall physical performance. It supports sustained energy levels, improved muscle function, and an enhanced quality of life, making it a valuable tool for preventative care and longevity.